Wat Traimit (วัดไตรมิตรวิทยารามวรวิหาร) is known for its giant Buddha image made from solid gold and weighing about 5.5 tonnes. The gold was hidden under plaster for centuries until being rediscovered in 1954.

Wat Pathum Khongkha (วัดปทุมคงคา) is an ancient wat, renovated and renamed Wat Sampheng during the King Rama I period.

Wat Chakkrawat (วัดจักรวรรดิราชาวาสมหาวิหาร) or Wat Sam Pluem (วัดสามปลื้ม)

Wat Samphanthawongsaram (วัดสัมพันธวงศาราม วรวิหาร) or Wat Ko (วัดเกาะ), a Dhammayuttika temple. Its name is the origin of the district's name and was Dan Beach Bradley's first residence in Thailand.

Many Chinese temples and shrines are also here, including:

Leng Buai Ia Shrine (ศาลเจ้าเล่งบ๊วยเอี๊ยะ), the oldest shrine in the area, about 300 years old, is considered the oldest Teochew shrine in Thailand.
Ah Nia Geng Shrine (ศาลเจ้าอาเนี้ยเก็ง) or Chue Pui Nia Nia Shrine (ศาลเจ้าฉื่อปุยเนี่ยเนี้ย), a shrine to Kuan Yin.
Guan Yu Shrine (ศาลเจ้าพ่อกวนอู), shrine to Guan Yu and his horse Sek Tao, in Talat Khao.
Thien Fah Foundation (มูลนิธิเทียนฟ้า), the first foundation registered in Thailand, established to provide health care for the poor. Inside there is a Guan Yin shrine.
Bunyasamakhom Shrine (ศาลเจ้าโรงเจบุญสมาคม)
Chó-su-kong Shrine (ศาลเจ้าโจวซือก๋ง), a shrine to Qingshui, the oldest Hoklo shrine in Thailand, in Talat Noi, used to organize the largest Chinese vegetarian food festival in the country.

The most famous Chinese temple in the area, Wat Mangkon Kamalawat (วัดมังกรกมลาวาส), popularly known as Wat Leng Noei Yi(วัดเล่งเน่ยยี่), lies just outside the Samphanthawong boundary in the neighboring Pom Prap Sattru Phai District.

Festivals

Several Chinese festivals are held here yearly. Yaowarat Road is often closed to traffic during these periods.

Chinese New Year Festival (เทศกาลตรุษจีน) is the biggest festival with dragon dances, lion dances, and people dressed in red.
Mid-Autumn Festival (เทศกาลไหว้พระจันทร์) with shops selling mooncakes.
Chinese Vegetarian Food Festival (เทศกาลกินเจ) (1st to 9th day of 9th lunar month) is a nine-day period when many Chinese practice vegetarianism and dress in white. All over Yaowarat Road, vegetarian food stalls with yellow flags and the Chinese character ? in red can be seen. Some foods look like meat but are made from soybeans.

Transportation

MRT Blue Line
BL29 Wat Mangkon